Auflistung nach Schlagwort "Heterologous expression"

Auflistung nach Schlagwort "Heterologous expression"

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  • The cycloaspeptides: Uncovering a new model for methylated nonribosomal peptide biosynthesis 
    De Mattos-Shipley, Kate M.J.; Greco, Claudio; Heard, David M.; Hough, Gemma; Mulholland, Nicholas P.; Vincent, Jason L.; Micklefield, Jason; Simpson, Thomas J.; Willis, Christine L.; Cox, Russell J.; Bailey, Andrew M. (Cambridge : Royal Society of Chemistry, 2018)
    The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the reported insecticidal activity of the minor metabolite, ...
  • Heterologous Expression, Purification, and Biochemical Characterization of α-Humulene Synthase from Zingiber zerumbet Smith 
    Alemdar, Semra; Hartwig, Steffen; Frister, Thore; König, Jan Christoph; Scheper, Thomas; Beutel, Sascha (New York City, NY : Springer Humana Press Inc., 2016)
    The α-humulene synthase from Zingiber zerumbet Smith was expressed as a polyhistidine-tagged protein in an E. coli BL21(DE3) strain. Induction time and inductor (isopropyl-β-D-thiogalactopyranoside) concentration were ...
  • Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis 
    Williams, Katherine; Szwalbe, Agnieszka J.; Mulholland, Nicholas P.; Vincent, Jason L.; Bailey, Andrew M.; Willis, Christine L.; Simpson, Thomas J.; Cox, Russell J. (Weinheim : Wiley-VCH Verlag, 2016)
    Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9-membered carbocycles with one or two fused maleic anhydride moieties. The biosynthesis of byssochlamic acid (a ...
  • Natural products isolation from Trichoderma reesei 
    Shenouda, Mary Labib Kamel Labib (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2022)
    The focus of the present work is to develop Trichoderma reesei as a heterologous host for the production of natural products and to explore the biosynthetic potential of this fungus by expressing one of its cryptic PKS-NRPS ...
  • Oxidative steps during the biosynthesis of squalestatin S1 
    Lebe, Karen E.; Cox, Russell J. (Cambridge : Royal Society of Chemistry, 2018)
    The squalestatins are a class of highly complex fungal metabolites which are potent inhibitors of squalene synthase with potential use in the control of cholesterol biosynthesis. Little is known of the chemical steps ...